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Increased Striatal Injury and Behavioral Deficits after Intracerebral Hemorrhage in Hemopexin Knockout Mice
OBJECT: Heme toxicity may contribute to the pathogenesis of intracerebral hemorrhage. The primary defense against extracellular heme is provided by hemopexin, a serum and neuronal glycoprotein that binds it with very high affinity and mitigates its pro-oxidant effect. In the present study, we tested...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061252/ https://ncbi.nlm.nih.gov/pubmed/21128737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2010.10.JNS10861 |
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