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Iron Regulatory Protein-2 Knockout Increases Perihematomal Ferritin Expression and Cell Viability after Intracerebral Hemorrhage

Iron is deposited in perihematomal tissue after an intracerebral hemorrhage (ICH), and may contribute to oxidative injury. Cell culture studies have demonstrated that enhancing ferritin expression by targeting iron regulatory protein (IRP) binding activity reduces cellular vulnerability to iron and...

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Autors principals: Chen, Mai, Awe, Olatilewa O., Chen-Roetling, Jing, Regan, Raymond F.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903222/
https://ncbi.nlm.nih.gov/pubmed/20399759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.04.018
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