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Increased Striatal Injury and Behavioral Deficits after Intracerebral Hemorrhage in Hemopexin Knockout Mice

OBJECT: Heme toxicity may contribute to the pathogenesis of intracerebral hemorrhage. The primary defense against extracellular heme is provided by hemopexin, a serum and neuronal glycoprotein that binds it with very high affinity and mitigates its pro-oxidant effect. In the present study, we tested...

詳細記述

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書誌詳細
主要な著者: Chen, Lifen, Zhang, Xuefeng, Chen-Roetling, Jing, Regan, Raymond F.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061252/
https://ncbi.nlm.nih.gov/pubmed/21128737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2010.10.JNS10861
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