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Transcription-coupled Nucleotide Excision Repair: New Insights Revealed by Genomic Approaches

Elongation of RNA polymerase II (Pol II) is affected by many factors including DNA damage. Bulky damage, such as lesions caused by ultraviolet (UV) radiation, arrests Pol II and inhibits gene transcription, and may lead to genome instability and cell death. Cells activate transcription-coupled nucle...

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Bibliografiske detaljer
Udgivet i:DNA Repair (Amst)
Main Authors: Duan, Mingrui, Speer, Rachel M., Ulibarri, Jenna, Liu, Ke Jian, Mao, Peng
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205993/
https://ncbi.nlm.nih.gov/pubmed/33894524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103126
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