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Transcription-coupled Nucleotide Excision Repair: New Insights Revealed by Genomic Approaches
Elongation of RNA polymerase II (Pol II) is affected by many factors including DNA damage. Bulky damage, such as lesions caused by ultraviolet (UV) radiation, arrests Pol II and inhibits gene transcription, and may lead to genome instability and cell death. Cells activate transcription-coupled nucle...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205993/ https://ncbi.nlm.nih.gov/pubmed/33894524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103126 |
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