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Transcription-coupled Nucleotide Excision Repair: New Insights Revealed by Genomic Approaches
Elongation of RNA polymerase II (Pol II) is affected by many factors including DNA damage. Bulky damage, such as lesions caused by ultraviolet (UV) radiation, arrests Pol II and inhibits gene transcription, and may lead to genome instability and cell death. Cells activate transcription-coupled nucle...
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| Veröffentlicht in: | DNA Repair (Amst) |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205993/ https://ncbi.nlm.nih.gov/pubmed/33894524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103126 |
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