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Transcription-coupled Nucleotide Excision Repair: New Insights Revealed by Genomic Approaches

Elongation of RNA polymerase II (Pol II) is affected by many factors including DNA damage. Bulky damage, such as lesions caused by ultraviolet (UV) radiation, arrests Pol II and inhibits gene transcription, and may lead to genome instability and cell death. Cells activate transcription-coupled nucle...

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Bibliografische gegevens
Gepubliceerd in:DNA Repair (Amst)
Hoofdauteurs: Duan, Mingrui, Speer, Rachel M., Ulibarri, Jenna, Liu, Ke Jian, Mao, Peng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205993/
https://ncbi.nlm.nih.gov/pubmed/33894524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103126
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