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Transcription-coupled Nucleotide Excision Repair: New Insights Revealed by Genomic Approaches

Elongation of RNA polymerase II (Pol II) is affected by many factors including DNA damage. Bulky damage, such as lesions caused by ultraviolet (UV) radiation, arrests Pol II and inhibits gene transcription, and may lead to genome instability and cell death. Cells activate transcription-coupled nucle...

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Dettagli Bibliografici
Pubblicato in:DNA Repair (Amst)
Autori principali: Duan, Mingrui, Speer, Rachel M., Ulibarri, Jenna, Liu, Ke Jian, Mao, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205993/
https://ncbi.nlm.nih.gov/pubmed/33894524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103126
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