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Genome-wide role of Rad26 in promoting transcription-coupled nucleotide excision repair in yeast chromatin

Transcription-coupled nucleotide excision repair (TC-NER) is an important DNA repair mechanism that removes RNA polymerase (RNAP)-stalling DNA damage from the transcribed strand (TS) of active genes. TC-NER deficiency in humans is associated with the severe neurological disorder Cockayne syndrome. I...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Duan, Mingrui, Selvam, Kathiresan, Wyrick, John J., Mao, Peng
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414089/
https://ncbi.nlm.nih.gov/pubmed/32690696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003868117
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