Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription

DNA adducts derived from carcinogenic polycyclic aromatic hydrocarbons like benzo[a]pyrene (B[a]P) and benzo[c]phenanthrene (B[c]Ph) impede replication and transcription, resulting in aberrant cell division and gene expression. Global nucleotide excision repair (NER) and transcription-coupled DNA re...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nadkarni, Aditi, Burns, John A., Gandolfi, Alberto, Chowdhury, Moinuddin A., Cartularo, Laura, Berens, Christian, Geacintov, Nicholas E., Scicchitano, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705403/
https://ncbi.nlm.nih.gov/pubmed/26559971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.685271
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