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Genetic instability associated with loop or stem–loop structures within transcription units can be independent of nucleotide excision repair

Simple sequence repeats (SSRs) are found throughout the genome, and under some conditions can change in length over time. Germline and somatic expansions of trinucleotide repeats are associated with a series of severely disabling illnesses, including Huntington's disease. The underlying mechani...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Burns, John A, Chowdhury, Moinuddin A, Cartularo, Laura, Berens, Christian, Scicchitano, David A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909459/
https://ncbi.nlm.nih.gov/pubmed/29474673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky110
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