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Genetic instability associated with loop or stem–loop structures within transcription units can be independent of nucleotide excision repair

Simple sequence repeats (SSRs) are found throughout the genome, and under some conditions can change in length over time. Germline and somatic expansions of trinucleotide repeats are associated with a series of severely disabling illnesses, including Huntington's disease. The underlying mechani...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Burns, John A, Chowdhury, Moinuddin A, Cartularo, Laura, Berens, Christian, Scicchitano, David A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909459/
https://ncbi.nlm.nih.gov/pubmed/29474673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky110
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