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Structural Basis of Metallo-β-lactamase Inhibition by N-Sulfamoylpyrrole-2-carboxylates
[Image: see text] Metallo-β-lactamases (MBLs) can efficiently catalyze the hydrolysis of all classes of β-lactam antibiotics except monobactams. While serine-β-lactamase (SBL) inhibitors (e.g., clavulanic acid, avibactam) are established for clinical use, no such MBL inhibitors are available. We rep...
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| Gepubliceerd in: | ACS Infect Dis |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical
Society
2021
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205225/ https://ncbi.nlm.nih.gov/pubmed/34003651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.1c00104 |
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