Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids

The exocrine pancreas, consisting of ducts and acini, is the site of origin of pancreatitis and pancreatic ductal adenocarcinoma (PDAC). Our understanding of the genesis and progression of human pancreatic diseases, including PDAC, is limited because of challenges in maintaining human acinar and duc...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Huang, Ling, Desai, Ridhdhi, Conrad, Daniel N., Leite, Nayara C., Akshinthala, Dipikaa, Lim, Christine Maria, Gonzalez, Raul, Muthuswamy, Lakshmi B., Gartner, Zev, Muthuswamy, Senthil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202734/
https://ncbi.nlm.nih.gov/pubmed/33915081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2021.03.022
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