Coordinated signaling of activating transcription factor 6α and inositol-requiring enzyme 1α regulates hepatic stellate cell-mediated fibrogenesis in mice

Liver injury and the unfolded protein response (UPR) are tightly linked, but their relationship differs with cell type and injurious stimuli. UPR initiation promotes hepatic stellate cell (HSC) activation and fibrogenesis, but the underlying mechanisms are unclear. Despite the complexity and overlap...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Gastrointest Liver Physiol
Hoofdauteurs: Xue, Fei, Lu, Jianwen, Buchl, Samuel C., Sun, Liankang, Shah, Vijay H., Malhi, Harmeet, Maiers, Jessica L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202196/
https://ncbi.nlm.nih.gov/pubmed/33728997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00453.2020
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