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On and off controls within dynein–dynactin on native cargoes
The dynein–dynactin nanomachine transports cargoes along microtubules in cells. Why dynactin interacts separately with the dynein motor and also with microtubules is hotly debated. Here we disrupted these interactions in a targeted manner on phagosomes extracted from cells, followed by optical trapp...
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| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8201952/ https://ncbi.nlm.nih.gov/pubmed/34074788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2103383118 |
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