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Assembly and activation of dynein–dynactin by the cargo adaptor protein Hook3

Metazoan cytoplasmic dynein moves processively along microtubules with the aid of dynactin and an adaptor protein that joins dynein and dynactin into a stable ternary complex. Here, we examined how Hook3, a cargo adaptor involved in Golgi and endosome transport, forms a motile dynein–dynactin comple...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Schroeder, Courtney M., Vale, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970328/
https://ncbi.nlm.nih.gov/pubmed/27482052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604002
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