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Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

Cytoplasmic dynein drives the majority of minus end-directed vesicular and organelle motility in the cell. However, it remains unclear how dynein is spatially and temporally regulated given the variety of cargo that must be properly localized to maintain cellular function. Recent work has suggested...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Olenick, Mara A., Tokito, Mariko, Boczkowska, Malgorzata, Dominguez, Roberto, Holzbaur, Erika L. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000072/
https://ncbi.nlm.nih.gov/pubmed/27365401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738211
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