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Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

Cytoplasmic dynein drives the majority of minus end-directed vesicular and organelle motility in the cell. However, it remains unclear how dynein is spatially and temporally regulated given the variety of cargo that must be properly localized to maintain cellular function. Recent work has suggested...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Olenick, Mara A., Tokito, Mariko, Boczkowska, Malgorzata, Dominguez, Roberto, Holzbaur, Erika L. F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000072/
https://ncbi.nlm.nih.gov/pubmed/27365401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738211
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