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Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

Cytoplasmic dynein drives the majority of minus end-directed vesicular and organelle motility in the cell. However, it remains unclear how dynein is spatially and temporally regulated given the variety of cargo that must be properly localized to maintain cellular function. Recent work has suggested...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Olenick, Mara A., Tokito, Mariko, Boczkowska, Malgorzata, Dominguez, Roberto, Holzbaur, Erika L. F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000072/
https://ncbi.nlm.nih.gov/pubmed/27365401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738211
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