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Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes
Cytoplasmic dynein is a molecular motor that transports a large variety of cargoes (e.g., organelles, messenger RNAs, and viruses) along microtubules over long intracellular distances. The dynactin protein complex is important for dynein activity in vivo, but its precise role has been unclear. Here,...
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| Veröffentlicht in: | Science |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224444/ https://ncbi.nlm.nih.gov/pubmed/25035494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1254198 |
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