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Differential effects of the dynein-regulatory factor Lissencephaly-1 on processive dynein-dynactin motility

Cytoplasmic dynein is the primary minus-end–directed microtubule motor protein in animal cells, performing a wide range of motile activities, including transport of vesicular cargos, mRNAs, viruses, and proteins. Lissencephaly-1 (LIS1) is a highly conserved dynein-regulatory factor that binds direct...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gutierrez, Pedro A., Ackermann, Bryce E., Vershinin, Michael, McKenney, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519373/
https://ncbi.nlm.nih.gov/pubmed/28576829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.790048
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