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Tyrosination of α‐tubulin controls the initiation of processive dynein–dynactin motility

Post‐translational modifications (PTMs) of α/β‐tubulin are believed to regulate interactions with microtubule‐binding proteins. A well‐characterized PTM involves in the removal and re‐ligation of the C‐terminal tyrosine on α‐tubulin, but the purpose of this tyrosination–detyrosination cycle remains...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: McKenney, Richard J, Huynh, Walter, Vale, Ronald D, Sirajuddin, Minhajuddin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888239/
https://ncbi.nlm.nih.gov/pubmed/26968983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593071
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