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Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin

Dynactin, a large multisubunit complex, is required for intracellular transport by dynein; however, its cellular functions and mechanism of action are not clear. Prior studies suggested that dynactin increases dynein processivity by tethering the motor to the microtubule through its own microtubule...

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Detalhes bibliográficos
Main Authors: Kardon, Julia R., Reck-Peterson, Samara L., Vale, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657088/
https://ncbi.nlm.nih.gov/pubmed/19293377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900976106
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