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Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae

The motor protein cytoplasmic dynein is responsible for most of the minus-end-directed microtubule traffic within cells. Dynein contains four evolutionarily conserved AAA (ATPase associated with various cellular activities) domains that are thought to bind nucleotide; the role of nucleotide binding...

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Detalhes bibliográficos
Main Authors: Reck-Peterson, Samara L., Vale, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC341754/
https://ncbi.nlm.nih.gov/pubmed/14755060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2637011100
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