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A mathematical understanding of how cytoplasmic dynein walks on microtubules

Cytoplasmic dynein 1 (hereafter referred to simply as dynein) is a dimeric motor protein that walks and transports intracellular cargos towards the minus end of microtubules. In this article, we formulate, based on physical principles, a mechanical model to describe the stepping behaviour of cytopla...

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Principais autores: L. Trott, M. Hafezparast, A. Madzvamuse
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2018-01-01
Serija:Royal Society Open Science
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Online dostop:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171568
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