mRNA Expression of SMPD1 Encoding Acid Sphingomyelinase Decreases upon Antidepressant Treatment

Major depressive disorder (MDD) is a severe psychiatric condition with key symptoms of low mood and lack of motivation, joy, and pleasure. Recently, the acid sphingomyelinase (ASM)/ceramide system has been implicated in the pathogenesis of MDD. ASM is a lysosomal glycoprotein that catalyzes the hydr...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Rhein, Cosima, Zoicas, Iulia, Marx, Lena M., Zeitler, Stefanie, Hepp, Tobias, von Zimmermann, Claudia, Mühle, Christiane, Richter-Schmidinger, Tanja, Lenz, Bernd, Erim, Yesim, Reichel, Martin, Gulbins, Erich, Kornhuber, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198802/
https://ncbi.nlm.nih.gov/pubmed/34071826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115700
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