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Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls

By catalyzing the hydrolysis of sphingomyelin into ceramide, acid sphingomyelinase (ASM) changes the local composition of the plasma membrane with effects on receptor-mediated signaling. Altered enzyme activities have been noted in common human diseases, including alcohol dependence. However, the un...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Mühle, Christiane, Weinland, Christian, Gulbins, Erich, Lenz, Bernd, Kornhuber, Johannes
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320816/
https://ncbi.nlm.nih.gov/pubmed/30551571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19124028
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