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Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls

By catalyzing the hydrolysis of sphingomyelin into ceramide, acid sphingomyelinase (ASM) changes the local composition of the plasma membrane with effects on receptor-mediated signaling. Altered enzyme activities have been noted in common human diseases, including alcohol dependence. However, the un...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mühle, Christiane, Weinland, Christian, Gulbins, Erich, Lenz, Bernd, Kornhuber, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320816/
https://ncbi.nlm.nih.gov/pubmed/30551571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19124028
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