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Characterization of Acid Sphingomyelinase Activity in Human Cerebrospinal Fluid

BACKGROUND: As a key enzyme in sphingolipid metabolism, acid sphingomyelinase (ASM) is involved in the regulation of cell fate and signaling via hydrolysis of sphingomyelin to form ceramide. While increased activity of the lysosomal form has been associated with various pathological conditions, ther...

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Detalhes bibliográficos
Main Authors: Mühle, Christiane, Huttner, Hagen B., Walter, Silke, Reichel, Martin, Canneva, Fabio, Lewczuk, Piotr, Gulbins, Erich, Kornhuber, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642176/
https://ncbi.nlm.nih.gov/pubmed/23658784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062912
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