Characterization of Acid Sphingomyelinase Activity in Human Cerebrospinal Fluid

BACKGROUND: As a key enzyme in sphingolipid metabolism, acid sphingomyelinase (ASM) is involved in the regulation of cell fate and signaling via hydrolysis of sphingomyelin to form ceramide. While increased activity of the lysosomal form has been associated with various pathological conditions, ther...

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Главные авторы: Mühle, Christiane, Huttner, Hagen B., Walter, Silke, Reichel, Martin, Canneva, Fabio, Lewczuk, Piotr, Gulbins, Erich, Kornhuber, Johannes
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642176/
https://ncbi.nlm.nih.gov/pubmed/23658784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062912
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