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Functional Implications of Novel Human Acid Sphingomyelinase Splice Variants
BACKGROUND: Acid sphingomyelinase (ASM) hydrolyses sphingomyelin and generates the lipid messenger ceramide, which mediates a variety of stress-related cellular processes. The pathological effects of dysregulated ASM activity are evident in several human diseases and indicate an important functional...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338701/ https://ncbi.nlm.nih.gov/pubmed/22558155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035467 |
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