A carregar...

The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice

Human and murine studies identified the lysosomal enzyme acid sphingomyelinase (ASM) as a target for antidepressant therapy and revealed its role in the pathophysiology of major depression. In this study, we generated a mouse model with overexpression of Asm (Asm-tg(fb)) that is restricted to the fo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cells
Main Authors: Zoicas, Iulia, Schumacher, Fabian, Kleuser, Burkhard, Reichel, Martin, Gulbins, Erich, Fejtova, Anna, Kornhuber, Johannes, Rhein, Cosima
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290754/
https://ncbi.nlm.nih.gov/pubmed/32443534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9051244
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!