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Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls

By catalyzing the hydrolysis of sphingomyelin into ceramide, acid sphingomyelinase (ASM) changes the local composition of the plasma membrane with effects on receptor-mediated signaling. Altered enzyme activities have been noted in common human diseases, including alcohol dependence. However, the un...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Mühle, Christiane, Weinland, Christian, Gulbins, Erich, Lenz, Bernd, Kornhuber, Johannes
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320816/
https://ncbi.nlm.nih.gov/pubmed/30551571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19124028
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