mRNA Expression of SMPD1 Encoding Acid Sphingomyelinase Decreases upon Antidepressant Treatment

Major depressive disorder (MDD) is a severe psychiatric condition with key symptoms of low mood and lack of motivation, joy, and pleasure. Recently, the acid sphingomyelinase (ASM)/ceramide system has been implicated in the pathogenesis of MDD. ASM is a lysosomal glycoprotein that catalyzes the hydr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Rhein, Cosima, Zoicas, Iulia, Marx, Lena M., Zeitler, Stefanie, Hepp, Tobias, von Zimmermann, Claudia, Mühle, Christiane, Richter-Schmidinger, Tanja, Lenz, Bernd, Erim, Yesim, Reichel, Martin, Gulbins, Erich, Kornhuber, Johannes
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198802/
https://ncbi.nlm.nih.gov/pubmed/34071826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115700
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