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Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor
The astacin protease Meprin β represents an emerging target for drug development due to its potential involvement in disorders such as acute and chronic kidney injury and fibrosis. Here, we elaborate on the structural basis of inhibition by a specific Meprin β inhibitor. Our analysis of the crystal...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8197800/ https://ncbi.nlm.nih.gov/pubmed/34073350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115651 |
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