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Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

Incretins, endogenous polypeptide hormones released in response to food intake, potentiate insulin secretion from pancreatic β cells after oral glucose ingestion (the incretin effect). This response is signaled by the two peptide hormones glucose-dependent insulinotropic polypeptide (GIP) (also know...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Parthier, Christoph, Kleinschmidt, Martin, Neumann, Piotr, Rudolph, Rainer, Manhart, Susanne, Schlenzig, Dagmar, Fanghänel, Jörg, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich, Stubbs, Milton T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955799/
https://ncbi.nlm.nih.gov/pubmed/17715056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706404104
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