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Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant (18)F-Labelled σ(2) Receptor Ligand
The σ(2) receptor (transmembrane protein 97), which is involved in cholesterol homeostasis, is of high relevance for neoplastic processes. The upregulated expression of σ(2) receptors in cancer cells and tissue in combination with the antiproliferative potency of σ(2) receptor ligands motivates the...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8196714/ https://ncbi.nlm.nih.gov/pubmed/34064122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115447 |
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