A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals

Serum bilirubin is associated with several clinical outcomes, including hypertension, type 2 diabetes (T2D), and drug metabolism. Here, we describe findings from our genome-wide association studies (GWAS) of serum (TBIL) using a generalized linear mixed model in West Africans (n = 1127), with adjust...

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Veröffentlicht in:NPJ Genom Med
Hauptverfasser: Chen, Guanjie, Adeyemo, Adebowale, Zhou, Jie, Doumatey, Ayo P., Bentley, Amy R., Ekoru, Kenneth, Shriner, Daniel, Rotimi, Charles N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196001/
https://ncbi.nlm.nih.gov/pubmed/34117260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-021-00208-6
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