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Phenotypic variance explained by local ancestry in admixed African Americans

We surveyed 26 quantitative traits and disease outcomes to understand the proportion of phenotypic variance explained by local ancestry in admixed African Americans. After inferring local ancestry as the number of African-ancestry chromosomes at hundreds of thousands of genotyped loci across all aut...

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Veröffentlicht in:Front Genet
Hauptverfasser: Shriner, Daniel, Bentley, Amy R., Doumatey, Ayo P., Chen, Guanjie, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625172/
https://ncbi.nlm.nih.gov/pubmed/26579196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00324
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