UGT1A1 is a major locus influencing bilirubin levels in African Americans

Total serum bilirubin is associated with several clinical outcomes, including cardiovascular disease, diabetes and drug metabolism. We conducted a genome-wide association study in 619 healthy unrelated African Americans in an attempt to replicate reported findings in Europeans and Asians and to iden...

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Autors principals: Chen, Guanjie, Ramos, Edward, Adeyemo, Adebowale, Shriner, Daniel, Zhou, Jie, Doumatey, Ayo P, Huang, Hanxia, Erdos, Michael R, Gerry, Norman P, Herbert, Alan, Bentley, Amy R, Xu, Huichun, Charles, Bashira A, Christman, Michael F, Rotimi, Charles N
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306855/
https://ncbi.nlm.nih.gov/pubmed/22085899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.206
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