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A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex

Epigenome-wide association studies of Alzheimer’s disease have highlighted neuropathology-associated DNA methylation differences, although existing studies have been limited in sample size and utilized different brain regions. Here, we combine data from six DNA methylomic studies of Alzheimer’s dise...

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Publicado no:Nat Commun
Main Authors: Smith, Rebecca G., Pishva, Ehsan, Shireby, Gemma, Smith, Adam R., Roubroeks, Janou A. Y., Hannon, Eilis, Wheildon, Gregory, Mastroeni, Diego, Gasparoni, Gilles, Riemenschneider, Matthias, Giese, Armin, Sharp, Andrew J., Schalkwyk, Leonard, Haroutunian, Vahram, Viechtbauer, Wolfgang, van den Hove, Daniel L. A., Weedon, Michael, Brokaw, Danielle, Francis, Paul T., Thomas, Alan J., Love, Seth, Morgan, Kevin, Walter, Jörn, Coleman, Paul D., Bennett, David A., De Jager, Philip L., Mill, Jonathan, Lunnon, Katie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192929/
https://ncbi.nlm.nih.gov/pubmed/34112773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23243-4
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