An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

A growing number of epigenome-wide association studies have demonstrated a role for DNA methylation in the brain in Alzheimer's disease. With the aim of exploring peripheral biomarker potential, we have examined DNA methylation patterns in whole blood collected from 284 individuals in the AddNe...

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Detaylı Bibliyografya
Yayımlandı:Neurobiol Aging
Asıl Yazarlar: Roubroeks, Janou A.Y., Smith, Adam R., Smith, Rebecca G., Pishva, Ehsan, Ibrahim, Zina, Sattlecker, Martina, Hannon, Eilis J., Kłoszewska, Iwona, Mecocci, Patrizia, Soininen, Hilkka, Tsolaki, Magda, Vellas, Bruno, Wahlund, Lars-Olof, Aarsland, Dag, Proitsi, Petroula, Hodges, Angela, Lovestone, Simon, Newhouse, Stephen J., Dobson, Richard J.B., Mill, Jonathan, van den Hove, Daniël L.A., Lunnon, Katie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7649340/
https://ncbi.nlm.nih.gov/pubmed/32745807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.06.023
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