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Investigation of the biological functions of heparan sulfate using a chemoenzymatic synthetic approach

Heparan sulfate (HS) is a highly sulfated polysaccharide playing essential physiological and pathophysiological roles in the animal kingdom. Heparin, a highly sulfated form of HS, is a widely used anticoagulant drug. Isolated from biological sources, both heparin and HS are polysaccharide mixtures w...

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Vydáno v:RSC Chem Biol
Hlavní autoři: Wang, Zhangjie, Arnold, Katelyn, Dhurandhare, Vijay Manohar, Xu, Yongmei, Liu, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: RSC 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190904/
https://ncbi.nlm.nih.gov/pubmed/34179782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cb00199f
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