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Directing the biological activities of heparan sulfate oligosaccharides using a chemoenzymatic approach
Heparan sulfate (HS) and heparin are highly sulfated polysaccharides exhibiting essential physiological functions. The sulfation patterns determine the functional selectivity for HS and heparin. Chemical synthesis of HS, especially those larger than a hexasaccharide, remains challenging. Enzymatic s...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230279/ https://ncbi.nlm.nih.gov/pubmed/21835782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwr109 |
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