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Directing the biological activities of heparan sulfate oligosaccharides using a chemoenzymatic approach
Heparan sulfate (HS) and heparin are highly sulfated polysaccharides exhibiting essential physiological functions. The sulfation patterns determine the functional selectivity for HS and heparin. Chemical synthesis of HS, especially those larger than a hexasaccharide, remains challenging. Enzymatic s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230279/ https://ncbi.nlm.nih.gov/pubmed/21835782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwr109 |
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