Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

Heparan sulfate is a sulfated glycan that exhibits essential physiological functions. Interrogation of the specificity of heparan sulfate-mediated activities demands a library of structurally defined oligosaccharides. Chemical synthesis of large heparan sulfate oligosaccharides remains challenging....

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Autores principales: Liu, Renpeng, Xu, Yongmei, Chen, Miao, Weïwer, Michel, Zhou, Xianxuan, Bridges, Arlene S., DeAngelis, Paul L., Zhang, Qisheng, Linhardt, Robert J., Liu, Jian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962522/
https://ncbi.nlm.nih.gov/pubmed/20729556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159152
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