Fluorous-Assisted Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides

[Image: see text] The chemoenzymatic synthesis of heparan sulfate tetrasaccharide (1) and hexasaccharide (2) with a fluorous tag attached at the reducing end is reported. The fluorous tert-butyl dicarbonate ((F)Boc) tag did not interfere with enzymatic recognition for both elongation and specific su...

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Autores principales: Cai, Chao, Dickinson, Demetria M., Li, Lingyun, Masuko, Sayaka, Suflita, Matt, Schultz, Victor, Nelson, Shawn D., Bhaskar, Ujjwal, Liu, Jian, Linhardt, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998769/
https://ncbi.nlm.nih.gov/pubmed/24697306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol500738g
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