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Towards the chemoenzymatic synthesis of heparan sulfate oligosaccharides: Oxidative cleavage of p-nitrophenyl group with ceric ammonium salts

We have developed an efficient chemoenzymatic synthesis of heparan sulfate oligosaccharides employing the para-nitrophenyl (p-NP) β-glucuronide as an acceptor compatible with enzymatic elongation and one that significantly simplifies oligosaccharide purification on C-18 resin. Employing ceric ammoni...

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Detalhes bibliográficos
Main Authors: Cai, Chao, Li, Lingyun, Harvey, Cate, Liu, Jian, Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733400/
https://ncbi.nlm.nih.gov/pubmed/23929984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.06.044
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