A Novel Stable Isotope Approach Demonstrates Surprising Degree of Age-Related Decline in Skeletal Muscle Collagen Proteostasis

Age-related deterioration in turnover of collagen proteins accelerates extracellular matrix fibrosis and hinders adaptation to external stimuli. This project sought to understand factors that increase skeletal muscle fibrosis with age by studying what we term the dynamic protein pool. We hypothesize...

詳細記述

保存先:
書誌詳細
出版年:Function (Oxf)
主要な著者: Abbott, Claire B, Lawrence, Marcus M, Kobak, Kamil A, Lopes, Erika Barboza Prado, Peelor, Frederick F, Donald, Elizabeth J, Van Remmen, Holly, Griffin, Timothy M, Miller, Benjamin F
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2021
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187230/
https://ncbi.nlm.nih.gov/pubmed/34124684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/function/zqab028
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