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A Novel Stable Isotope Approach Demonstrates Surprising Degree of Age-Related Decline in Skeletal Muscle Collagen Proteostasis

Age-related deterioration in turnover of collagen proteins accelerates extracellular matrix fibrosis and hinders adaptation to external stimuli. This project sought to understand factors that increase skeletal muscle fibrosis with age by studying what we term the dynamic protein pool. We hypothesize...

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Detalhes bibliográficos
Publicado no:Function (Oxf)
Main Authors: Abbott, Claire B, Lawrence, Marcus M, Kobak, Kamil A, Lopes, Erika Barboza Prado, Peelor, Frederick F, Donald, Elizabeth J, Van Remmen, Holly, Griffin, Timothy M, Miller, Benjamin F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187230/
https://ncbi.nlm.nih.gov/pubmed/34124684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/function/zqab028
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