A Novel Stable Isotope Approach Demonstrates Surprising Degree of Age-Related Decline in Skeletal Muscle Collagen Proteostasis

Age-related deterioration in turnover of collagen proteins accelerates extracellular matrix fibrosis and hinders adaptation to external stimuli. This project sought to understand factors that increase skeletal muscle fibrosis with age by studying what we term the dynamic protein pool. We hypothesize...

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Bibliografiska uppgifter
I publikationen:Function (Oxf)
Huvudupphovsmän: Abbott, Claire B, Lawrence, Marcus M, Kobak, Kamil A, Lopes, Erika Barboza Prado, Peelor, Frederick F, Donald, Elizabeth J, Van Remmen, Holly, Griffin, Timothy M, Miller, Benjamin F
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2021
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187230/
https://ncbi.nlm.nih.gov/pubmed/34124684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/function/zqab028
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