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THE DECLINE OF PROTEOSTASIS IN AGING
The components of the proteostasis networks, chaperones and proteolytic systems, are responsible for the maintenance of a healthy and functional proteome. Malfunctioning of the proteasome and autophagy, the two main proteolytic systems that contribute to proteostasis, occurs with age. In this sessio...
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| Publicado en: | Innov Aging |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6226949/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.1440 |
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