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THE DECLINE OF PROTEOSTASIS IN AGING

The components of the proteostasis networks, chaperones and proteolytic systems, are responsible for the maintenance of a healthy and functional proteome. Malfunctioning of the proteasome and autophagy, the two main proteolytic systems that contribute to proteostasis, occurs with age. In this sessio...

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Dades bibliogràfiques
Publicat a:Innov Aging
Autor principal: Cuervo, A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226949/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.1440
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