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Proteostasis and the Aging Proteome in Health and Disease

The maintenance of the proteome is essential to preserve cell functionality and the ability to respond and adapt to the changing environment. This is regulated by the proteostasis network, a dedicated set of molecular components comprised of molecular chaperones and protein clearance mechanisms, reg...

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Bibliografske podrobnosti
Main Authors: Morimoto, Richard I., Cuervo, Ana Maria
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022129/
https://ncbi.nlm.nih.gov/pubmed/24833584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu049
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