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Proteostasis and the Aging Proteome in Health and Disease

The maintenance of the proteome is essential to preserve cell functionality and the ability to respond and adapt to the changing environment. This is regulated by the proteostasis network, a dedicated set of molecular components comprised of molecular chaperones and protein clearance mechanisms, reg...

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Detalhes bibliográficos
Main Authors: Morimoto, Richard I., Cuervo, Ana Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022129/
https://ncbi.nlm.nih.gov/pubmed/24833584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu049
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