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Proteostasis and the Aging Proteome in Health and Disease

The maintenance of the proteome is essential to preserve cell functionality and the ability to respond and adapt to the changing environment. This is regulated by the proteostasis network, a dedicated set of molecular components comprised of molecular chaperones and protein clearance mechanisms, reg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Morimoto, Richard I., Cuervo, Ana Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022129/
https://ncbi.nlm.nih.gov/pubmed/24833584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu049
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